Search on: CARCINOID HEART DISEASE 
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Descriptor English:   Carcinoid Heart Disease 
Descriptor Spanish:   Cardiopatía Carcinoide 
Descriptor Portuguese:   Doença Cardíaca Carcinoide 
Tree Number:   C04.557.465.625.650.200.500.205
C04.557.470.200.025.200.500.205
C04.557.580.625.650.200.500.205
C14.280.104
Definition English:   Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation. 
History Note English:   91(75)(64-72); was see under MALIGNANT CARCINOID SYNDROME 1964-90 (Prov 1964-72) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   2318 
Unique Identifier:   D002275 

Occurrence in VHL:
 

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